Chromokinesin
WebMay 12, 2024 · Chromokinesins are motor proteins that interact with both microtubules and chromatin ( Mazumdar and Misteli, 2005; Vanneste et al., 2011 ). Two well-characterized chromokinesin genes in Drosophila are the kinesin-10–related motor Nod ( Theurkauf and Hawley, 1992) and the kinesin-4–related motor Klp3a ( Williams et al., 1995 ). WebJun 22, 2024 · The chromokinesin KIF22 generates forces that contribute to mitotic chromosome congression and alignment. Mutations in the α2 helix of the motor domain …
Chromokinesin
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WebChromokinesins are microtubule plus end–directed motor proteins that bind to chromosome arms. In Xenopus egg cell-free extracts, Xkid and Xklp1 are essential for … WebSep 21, 2005 · The human chromokinesin Kid/Kinesin-10 is a plus end-directed MT-based motor ( Shiroguchi et al ., 2003; Yajima et al ., 2003) that binds both MTs and chromosomes ( Tokai et al ., 1996 ). Kid has been reported to play an important role in chromosomal movement along MTs during prometaphase and metaphase.
WebSep 30, 2013 · Here we show that a quantum dot (Qdot) binding up to four Xenopus chromokinesin (Xkid) molecules behaved like a nanosize chromosome arm in the …
WebOct 8, 2024 · Chromokinesins are members of the kinesin superfamily that harbour a specific DNA-binding domain. The best characterized chromokinesins belong to the … WebApr 8, 2024 · This bias was impervious to the experimental attenuation of polar ejection forces on chromosome arms by RNAi against the chromokinesin Kif4a. Thus, kinetochore size is an important determinant of ...
WebThe chromokinesin KIF22 generates forces that contribute to mitotic chromosome congression and alignment. Mutations in the α2 helix of the motor domain of KIF22 have been identified in patients with abnormal skeletal development, and we report the identification of a patient with a novel mutation in the KIF22 tail.
WebJul 16, 1996 · The Kinesin-4 (formerly Chromokinesin/KIF4) family tree was obtained using the heuristic search method of PAUP v4.0b10 (Swofford, 2002), a maximum parsimony program, and random stepwise addition. The tree is one of two optimal trees that resulted from 600 trees that were built. The bootstrap values adjacent to the nodes are the … iq test theoryWebSep 21, 2011 · Interestingly, from its positioning on the chromosome arms, Hklp2 seems to restrict spindle pole separation. In the present review, we summarize the current knowledge of the function and regulation of the different kinesins associated with chromosome arms during cell division, including Hklp2 as a novel member of this so-called chromokinesin ... orchid dvdWebMar 16, 2024 · The chromokinesin KIF22 generates forces that contribute to mitotic chromosome congression and alignment. Mutations in the α2 helix of the motor domain … orchid dual matteWebGao J, Sai N, Wang C, et al. Overexpression of chromokinesin KIF4 inhibits proliferation of human gastric carcinoma cells both in vitro and in vivo. Tumour Biol. 2011;32(1):53–61. 20. Wu G, Zhou L, Khidr L, et al. A novel role of the chromokinesin Kif4A in DNA damage response. Cell Cycle. 2008;7(13):2013–2024. 21. iq test up to 160WebMar 6, 2015 · The chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindles. J. Cell Biol. 154 , 1135–1146 (2001) . iq test what is averageWebNational Center for Biotechnology Information iq test with instant free resultsWebThe chromokinesins are a subgroup of kinesin motors. Chromokinesins act in various steps of mitosis, including chromosome condensation, metaphase alignment, chromosome segregation, cytokinesis and they help maintain genome stability. iq test year 7