Cisplatin long term effects
WebTherapeutic efficacy of cisplatin-based treatment of late stage urothelial carcinoma (UC) is limited by chemoresistance. To elucidate underlying mechanisms and to develop new approaches for overcoming resistance, we generated long-term cisplatin treated (LTT) UC cell lines, characterised their cisplatin response, and determined the expression of … WebNov 16, 2016 · Factors influencing short- and long-term effects of cisplatin Overview of how different factors can influence long-term normal tissue effects after cisplatin (CDDP) treatment. CDDP causes DNA damage. Many cellular effects are mediated by p53 as part of the DNA damage response yielding long-term side effects.
Cisplatin long term effects
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WebThese side effects happen in more than 10 in 100 people (more than 10%). You might have one or more of them. They include: Increased risk of infection Increased risk of getting an infection is due to a drop in white blood cells. Symptoms include a change in temperature, aching muscles, headaches, feeling cold and shivery and generally unwell. WebNov 2, 2024 · Some long-term side effects have been linked to elevated platinum levels, such as: tingling or burning of extremities low sex hormones high cholesterol high blood …
WebConclusions: Renal function before and after cisplatin treatment is an important determinant of long-term Pt exposure. Known long-term effects of testicular cancer treatment, such as paraesthesia, hypogonadism, hypercholesterolaemia and hypertension, are associated with long-term circulating Pt exposure. WebJun 14, 2024 · Common long-term side effects of chemotherapy include early menopause and weight gain. Rare side effects include heart problems and leukemia. Learn about short-term effects of chemotherapy . Early menopause Some chemotherapy drugs can damage the ovaries and stop regular menstrual cycles (amenorrhea).
WebFeb 1, 2024 · Check with your doctor immediately if any of the following side effects occur: More common. Black, tarry stools blood in urine or stools burning, numbness, … WebNov 1, 2024 · Significant risks for long-term toxicities associated with cisplatin and platinum-based regimens were reported. The cumulative dose of cisplatin and …
WebFeb 1, 2024 · Cisplatin may cause serious kidney problems. Tell you doctor right away if you have blood in urine, change in frequency of urination or amount of urine, difficulty in …
WebThese side effects can include: Hair loss Mouth sores Loss of appetite Nausea and vomiting Diarrhea Increased chance of infections (from having too few white blood cells) Easy bruising or bleeding (from having too few blood platelets) Fatigue (extreme tiredness, often from having too few red blood cells) list of baby items to buy before deliveryWebLong-term vascular toxicities associated with chemotherapy include Raynaud's phenomenon, acute myocardial infarction and cerebrovascular events. Bleomycin is thought to be the most important drug in the pathogenesis of Raynaud's phenomenon, while cisplatin is the most likely agent involved in myocardial infarction. list of baby names 2022WebCisplatin is a platinum-based chemotherapeutic that has long since been effective against a variety of solid-cancers, substantially improving the five-year survival rates for cancer patients. Its use has also historically been limited by its adverse drug reactions, or cisplatin-induced toxicities (CITs). Of these reactions, cisplatin-induced nephrotoxicity (CIN), … images of painted brickWebThe application of esophagograms to evaluate early curative effects has a long history in China and has accumulated a lot of evidence. An esophagogram can show whether the outline of the esophagus is narrow and whether the esophageal mucosal folds are restored. ... Tang HR, et al. Long‐term results of paclitaxel plus cisplatin with concurrent ... images of painted birdhousesWebMay 20, 2024 · In two of these trials, researchers swapped out cisplatin—which has long been the standard chemotherapy for this cancer but can cause long-term side effects, … images of painted bookshelvesWebTherapeutic efficacy of cisplatin-based treatment of late stage urothelial carcinoma (UC) is limited by chemoresistance. To elucidate underlying mechanisms and to develop new … images of painted bathroom cabinetsWebFatigue, nausea: Fatigue, nausea and vomiting are very common after chemotherapy treatments with cisplatin. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help 5.7k views Reviewed >2 years ago Thank Dr. Luis Villaplana and another doctor agree 2 thanks A 43-year-old member asked: images of painted brick houses