Hes1 motif
Witryna10 mar 2011 · HES1 is the most commonly described Notch/CSL target gene 17 and appears to contribute to T-cell leukemogenesis. 20 It encodes a basic helix-loop-helix … Witryna8 gru 2024 · The Notch signaling factor HES1 (hairy and enhancer of split 1) is a well-known repressor of proneural genes, and HES1 ultradian oscillation is essential for …
Hes1 motif
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WitrynaDescription: Homo sapiens hes family bHLH transcription factor 1 (HES1), mRNA. (from RefSeq NM_005524) RefSeq Summary (NM_005524): This protein belongs to the … WitrynaNational Center for Biotechnology Information
HES1 influences the maintenance of certain stem cells and progenitor cells. Specifically, HES1 influences the timing of differentiation by repressing bHLH activators, and determines binary cell fate. HES1 has been shown to play a large role in both the nervous, and digestive systems. HES1 has been … Zobacz więcej Transcription factor HES1 (hairy and enhancer of split-1) is a protein that is encoded by the Hes1 gene, and is the mammalian homolog of the hairy gene in Drosophila. HES1 is one of the seven members of … Zobacz więcej There are three conserved domains in Hes genes that impart transcriptional functions: the bHLH domain, the Orange domain, and the WRPW motif. Hes genes differ from other bHLH factors in that they have a proline residue in the middle of the basic DNA binding … Zobacz więcej • Takebayashi K, Sasai Y, Sakai Y, Watanabe T, Nakanishi S, Kageyama R (1994). "Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements" Zobacz więcej Similarly to other HES proteins, Hes1 has been shown to interact with the co-repressors encoded by the Transducin-like E(spl) (TLE) genes and the Groucho-related gene (Grg), both homologs of the Drosophila groucho. Because Groucho in Drosophila … Zobacz więcej • HES1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from the United States National Library of Medicine, which is in the public domain. Zobacz więcej Witryna8 mar 2010 · To confirm HES1 interaction with the N-box motif in genomic DNA of whole cells, we performed a chromatin immunoprecipitation (ChIP) assay using FLAG …
Witryna20 lut 2024 · We show that HES1 is mono-ubiquitinated on a highly-conserved lysine residue that is located within a FA-like recognition motif. HES1 modification is … WitrynaHes1 Synonyms Hes-1 Organism names Organism Mus musculus (Mouse) Taxonomic identifier 10090 NCBI Taxonomic lineage Eukaryota > Metazoa > Chordata > …
Witryna25 paź 2006 · Hes1 and Hes5 are transcriptional repressors, the expression of which is activated in response to Notch stimulation. They act by recruiting …
Witryna13 lip 2012 · HES stand for those proteins which show homology to the Drosophila hairy and Enhancer of split basic helix-loop-helix (bHLH) proteins, the first reported proteins … 動画 dvd 作成 アプリWitrynaFunction. Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the … a.v.v キッズWitrynaHes1 is a mammalian basic helix-loop-helix transcriptional repressor that inhibits neuronal differentiation together with corepressors of the Groucho (Gro)/Transducin … 動画 dvd 書き込み ソフト